Monday, 9th May 14th Australian Peptide Conference 2022
Breakfast
7:30AM - 8:30AM
Monday, 9th May
Peptide Chemistry I
8:30AM - 10:30AM
Monday, 9th May
Chairs: Lara Malins & Christian Hackenberger
Sponsored by:
- Exploiting Thioamide Reactivity in Peptide Synthesis - Craig Hutton
- Controlling cyclic peptide conformation using stereoselective fluorination chemistry - Luke Hunter
- Cyclic and bicyclic peptides as inhibitors of viral proteases - Christoph Nitsche
- New methods for the chemoselective functionalization of peptides - Caroline Proulx
- Peptides as versatile probes for interrogating protein architecture and function - Yu Heng Lau
Morning Tea
10:30AM - 11:00AM
Monday, 9th May
Pharmacology & Signalling
11:00AM - 1:00PM
Monday, 9th May
Chairs: Kate Schroder & Ross Bathgate
Sponsored by:
- The activation mechanisms of PINK1 and Parkin during mitophagy - David Komander
- Dissecting peptide GPCR signalling networks in human cardiac organoids - Simon Foster
- The role of the Ghrelin Receptor in transforming dopamine pharmacology - Sebastian GB Furness
- Sugar and slice: bacterial glycosyltransferases and proteases dictate host responses to infection. - Jaclyn Pearson
- Structural basis for selectivity, allostery and bias at the adenosine receptors - Alisa Glukhova
Lunch
1:00PM - 2:00PM
Monday, 9th May
Rapid Fire Session
2:00PM - 3:40PM
Monday, 9th May
Chairs: Katrina Jolliffe & David James
- Superbug kryptonite? A peptide-based immunotherapeutic that enhances neutrophil clearance of Staphylococcus aureus through GPCR activation - Jennifer A. E Payne
- Global mapping of the platelet targetome of naturally-occurring isothiocyanates reveals potent and potentially safer targets for antithrombotic treatment - Xuyu Liu
- Development of a high affinity peptidomimetic inhibitor of the human sliding clamp PCNA - Aimee J Horsfall
- Probing and attacking Plasmodium parasites with aspartyl protease peptidomimetic inhibitors - Brad E Sleebs
- Self-cyclization as a general and efficient platform for peptide and protein macrocyclization - Yanni Chin
- Engineering of tick evasins as chemokine-targeted anti-inflammatory agents - Ram Prasad BHUSAL
- Three ways to take down cholesterol with peptides - Conan K Wang
- Poly(hydrophobic amino acids) as a Self-Adjuvanting Delivery System for Peptide Vaccines - Mariusz Skwarczynski
- Developing a novel antimicrobial peptide Laterocidine against pandrug-resistant Gram-negatives - Nitin Patil
- Cereblon-directing phenyl glutarimide PROTACs with improved degradation selectivity for janus kinase 2 - Lisa J Alcock
Afternoon tea
3:40PM - 4:15PM
Monday, 9th May
Centre of Excellence
4:15PM - 6:05PM
Monday, 9th May
Chairs: Norelle Daly & Richard Lewis
- Decoding and developing natural peptides: an overview of peptide chemistry at the Australian Research Council Centre of Excellence for Innovations in Peptide and Protein Science - Glenn F King
- Biosynthesis of nonribosomal peptide anticancer drugs - Gregory L Challis
- Development of peptide-based antimalarial drugs with selective entry into infected cells - Nicole Lawrence
- The safety of alternative proteins: proteomics studies of novel and emerging protein sources - Michelle Colgrave
- Applications of strained hydrocarbons for the synthesis of modified peptides - Lara R Malins
- Artificial peptides for anion recognition and sensing - Katrina Jolliffe
Dinner
6:05PM - 7:30PM
Monday, 9th May
Poster Session I and Drinks
7:30PM - 10:00PM
Monday, 9th May
Sponsored by:
- Molecular analysis of teneurin C-terminal associated peptide, and its physiological effects in the Sydney rock oyster (Saccostrea glomerta) - Tomer Abramov
- Small molecule probes for visualising Aβ42 monomer sequestration by macrocycle conjugates - Julius SP Adamson
- Photo dynamic activity of short peptide - Karrar Al Taief
- Evasins Engineering: A Promising Approach to Target Specific Chemokines - Pramod Aryal
- Investigating the importance of side chain dynamics of Y11 of neurotensin in activation of neurotensin receptor 1 - Kazem KA Asadollahi
- Testing the activity of cyclotides against soil nematodes - Abhishek Bajpai
- Potent bactericidal antimycobacterials targeting the chaperone ClpC1 based on the depsipeptide natural products ecumicin and ohmyungsamycin A - Isabel K Barter
- Cyclisation of Linear Peptides from Unmodified Starting Residues Using Reductive Amination Chemistry - Hayden Bell
- Hairpin peptides kill metastatic BRAF mutant melanoma cells that have acquired drug-resistance - Aurelie Benfield
- In vitro evolution of cyclic peptide inhibitors of acid-sensing ion channel 1a to produce neuroprotective drug candidates - Kimberley A Biggs
- Relaxin(g) your way through inflammatory and heart diseases: insight into a novel binding mechanism of H2 relaxin - Shatabdi Chakraborty
- Optimization of phosphotyrosine peptides that target the SH2 domain of SOCS1 and block substrate ubiquitination - Hao Chen
- Rational design of an A3B3 hetero hexameric alpha helical barrel - Joel J Chubb
- MacroConf – Dataset and computational workflows to assess cyclic peptide solution structures - Daniel Crusius
- Structural insights into the inhibition of the Chemokine activity by Tick Evasins - Shankar Devkota
- Discovery and structure-activity relationships of a novel antimicrobial agent by using structure-based virtual screening - Satish N Dighe
- Semisynthesis of mycobacterial lipoproteins - Joshua J Dilly
- Discovery and structure-function of a spider-venom peptide Ssp1a at hNaV1.2, hNaV1.3 and hNaV1.7 - Yashad Dongol
- Development of peptide based subunit vaccine for prevention of Tuberculosis - Viet Tram Duong
- Potent cyclic peptide inhibitors of FXIIa discovered by mRNA display with genetic code reprogramming - Sarah E. Fry
- Cyclic and stapled peptides for inhibiting the FANCM-RMI interaction at telomeres - Tianyi Gao
- The development of a peptide toolkit for C5aR1 interrogation - Declan M Gorman
- Expanding knowledge on the structure, function, and evolution of nettle caterpillar venom toxins - Mohaddeseh H Goudarzi
- Fatty-Acid Structurally Nanoengineered Peptide Polymers kill multidrug resistant bacteria. - Sara Hadjigol
- A Radical Approach to Unnatural Amino Acids - Joshua M Hammond
- Role of Peptide Flexibility in GPCR Agonism: a Molecular Dynamics Study - Herodion A Hartono
- Put a ring on it! The importance of the cyclic cystine knot motif for immunosuppressive effects of cyclotides - Peta J Harvey
- Towards the synthesis of covalent peptide inhibitors for CHIKV nsP2pro - Junming He
- Structures of a non-ribosomal peptide synthetase condensation domain suggest the basis of substrate selectivity - Candace YT Ho
- Unique pharmacological properties by α-conotoxin OmIA at α7 nAChRs - Thao Ho
- A step efficient Fmoc SPPS synthesis of daptomycin - Aimee J Horsfall
- Biosynthesis of the potent antitrypanosomal spoxazomicins A-C - Chuan Huang
- Stapled IGFBP-3 peptides for enhancing triple-negative breast cancer therapy - Tiancheng Huang
- A single point mutation drives efficient folding and enables high-resolution crystallographic analysis of bracelet cyclotides - Yen-Hua Crystal Huang
- Improving Pharmacological Landscape of Macrocyclic Peptides through Thioamide Substitution: A Bottom-up Approach - PRITHA GHOSH
- Determinants of IGF-II influencing stability and receptor binding and activation - Andrew Blyth
- Decoding the role of sugar tags on proteins linked to neurodegeneration - Santosh Dr Rudrawar
- Antiviral Cyclic Peptides Targeting the Main Protease of SARS-CoV-2 - Patrick Carlos